Laboratory of Frog Bioactive Peptides
He receveid his Master Degree in Pharmaceutical Biotechnology in 2013 at Sapienza University of Rome cum laude, and his PhD in Biochemistry in 2017 with a thesis entitled “Different approaches to optimize the antimicrobial properties of cationic peptides: substitution by non-coded amino acids and conjugation to nanoparticles”. His current research is focused on the characterization of the biological properties of natural bioactive compounds, in particular antimicrobial peptides and therapeutic proteins, and on different approaches to conjugate them to nanoparticle systems.
Post-Doc since 2017 at Sapienza University of Rome, Department of Biochemical Sciences A. Rossi Fanelli. She received her master degree in Cell Biology in 2014 at Sapienza University of Rome, and obtained her PhD in Biochemistry in 2017 with a doctoral thesis entitled “Effects of two L- to D-amino acid substitutions on the structural and functional properties of the antimicrobial peptide esculentin-1a(1-21)”. Her current research inerests are focused on the characterization of the biological properties of natural bioactive compounds, such as antimicrobial peptides, in mammalian cells, including their cytotoxic effect and their immunomodulatory activities.
Maria Rosa Loffredo
PhD student since 2016 at Sapienza University of Rome, Department of Biochemical Science
She obtained her master degree in Pharmaceutical Biotechnology in 2016, 110/110 cum laude. Her research is focused on the characterization of the mechanism(s) of action of the natural bioactive compounds with antimicrobial activity by fluorescence and spectroscopy assays.
Gabriele Nicasio Di Foggia
Undergraduate student in Drug Chemistry and Technology. The research project deals with the in vitro characterization of the antimicrobial and immunomodulatory properties of frog peptides and derivatives.